Ultima clasificación general correspondiente a domingo, 28 de mayo de 2023 Etapa 21 - Roma - Roma (126 Km)
| PUESTO | CORREDOR | EQUIPO | CAMISETA | TIEMPOS | DIFERENCIA |
|---|---|---|---|---|---|
1  |  Primoz Roglic (SLO) | TJV | 141 | 85:29:02 | 85:29:02 |
| 2 |  Geraint Howell Thomas (GBR) | IGD | 118 | 85:29:16 | +00:00:14 |
| 3 |  Joao Pedro Gonçalves Almeida (POR) | UAD | 211 | 85:30:17 | +00:01:15 |
| 4 |  Damiano Caruso (ITA) | TBV | 44 | 85:33:42 | +00:04:40 |
| 5 |  Thibaut Pinot (FRA) | GFC | 101 | 85:34:45 | +00:05:43 |
| 6 |  Thymen Arensman (NED) | IGD | 112 | 85:35:07 | +00:06:05 |
| 7 |  Edward Dunbar (IRL) | JAY | 193 | 85:36:32 | +00:07:30 |
| 8 |  Andreas Leknessund (NOR) | DSM | 181 | 85:36:33 | +00:07:31 |
| 9 |  Lennard Kämna (GER) | BOH | 56 | 85:36:48 | +00:07:46 |
| 10 |  Laurens de Plus (BEL) | IGD | 113 | 85:38:10 | +00:09:08 |
| 11 |  Einer Augusto Rubio (COL) | MOV | 155 | 85:39:45 | +00:10:43 |
| 12 | Ilan van Wilder (BEL) | SOQ | 7 | 85:41:00 | +00:11:58 |
| 13 | Santiago Buitrago (COL) | TBV | 43 | 85:41:23 | +00:12:21 |
| 14 |  Sepp Kuss (USA) | TJV | 146 | 85:42:11 | +00:13:09 |
| 15 | Aurélien Paret Peintre (FRA) | ACT | 15 | 85:43:15 | +00:14:13 |